Herpes vaccine candidate tracker

Every HSV (herpes-simplex-virus) vaccine candidate we track, ordered by how far it has progressed. Each row shows the current phase and the date we last verified it. Open a candidate for its full status and sources.

Candidate Developer Platform Target Approach Phase Updated
BNT163 BioNTech SE mRNA HSV-2 prophylactic phase 1
Trivalent gC2/gD2/gE2 mRNA (UPenn) University of Pennsylvania (Friedman & Weissman labs); licensed to BioNTech mRNA HSV-2 prophylactic preclinical
GEN-003 Genocea Biosciences protein subunit HSV-2 therapeutic discontinued
Herpevac (gD2 subunit, GSK) GlaxoSmithKline protein subunit HSV-2 prophylactic discontinued
mRNA-1608 Moderna (ModernaTX, Inc.) mRNA HSV-2 therapeutic discontinued
Theravax / Profavax (Rational Vaccines) Rational Vaccines (William Halford) live-attenuated both both discontinued